Three of the Welsh rugby regions have a chance to avenge the weekend's loss in the RBS 6 Nations, when they take on Irish opposition as the RaboDirect PRO12.
All three games are on Friday night as Cardiff Blues and Scarlets host Leinster and Connacht while Ospreys, the only Welsh team on the road, head to Ravenhill to play an Ulster side recently boosted by the contract extension of captain Johann Muller.
The Blues are looking to bolster the fortress status of the Arms Park, having won their last three games at the venue, with visiting European champions, Leinster, offering a stern assessment of its credentials.
Ulster took over the top of the table after round five and have remained there ever since, enjoying an 11-point lead, which could stand them in good stead during the international and European periods.
The last game on Friday night is at Rodney Parade where Treviso, who will be looking to build on an already impressive record against the Dragons.
The two Scottish teams both face away trips, Edinburgh Rugby to Munster on Saturday and Glasgow Warriors in Parma, to face Zebre, on Sunday.
Victory over Italian colleagues, Benetton Treviso, in the previous round lifted the Warriors to second place in the table, the highest position they"ve held all season while, conversely, Munster's loss to Cardiff Blues saw them drop out of the play-off zone. With just four points separating the second to sixth placed teams, the pressure on the top four is intensifying significantly. _
Munster have won four of their last five games in all competitions, but their home record varies wildly with the venue: winning their last nine fixtures at Thomond Park but losing their last two at Musgrave, where they host Edinburgh Rugby this weekend.
However, Munster have already beaten Edinburgh three times in all competitions this season, with the Scotsmen's last away win against Munster coming in 2006.